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Today she's 57 with an internet business, a live-in son, and menopause. Now how do you sell her drugs. P lasmatech Continued From Page 15 cal device equipment. Materials processed for the aerospace community include inflexible KaptonTM assemblies, fluoropolymers and composite honeycombs to enhance adhesion. The "60 inch web treater" was developed for modification of rolled goods to include wovens, non-wovens, films, foils and membranes. This system allows for extremely cost effective functionalization of films such as cyclic olefin copolymers and polystyrene ; for immunoassay microfluidic devices and customized modification of membranes and wovens for filtration separation chemistries. Work continues today for activating SpectraTM, ZylonTM and KevlarTM for the aerospace and defense industries. Airco BOC Coating Technology BOCCT ; purchased Plasma Science from Himont in 1994 to create a separate technology center to complement BOCCT's involvement in QLF silicon oxide barrier ; coatings. PECVD coatings were developed for scratch resistance on ophthalmologic products as well as automotive glass ; . stents for subsequent drug loading. Considerable work in the area is conducted for modification of microfluidic tools. Application examples include PECVD polystyrene coatings or creating specific amine functional sites. Additional work of interest is in activation of and even removal of ParyleneTM and the deposition of hydrogel-like films. PTS and 4th State have strong relationships with Stanford and Berkeley and affiliated research labs ; as well as many other academic institutions throughout the U.S. and the world. Students are welcome to work in the labs at a discounted fee. Continuing work with UCSF Berkeley bioengineering group includes PEGylation of UHMWPE implants for reducing wear and as presented at the 2005 BioInterface meeting, successful introduction of mercaptosilanes for functionalizing devices for the Stanford Genome Technology Center. With the strong R&D and incubator environment in the Bay Area, we find continual excitement in being privy to developments in the life science industry. And thanks to involvement in the Surfaces for Biomaterials Foundation, PTS is able to generate contacts with other technologists who share with us their successes and challenges in the industry. This networking greatly aids us in understanding different surface modification requirements, which allows us resources to solve complex customer issues often involving multiple surface modification methods. In addition, understanding other companies' surface modification technologies is critical in ensuring our customers' success using our technology. To conclude, over the past 25 years and through a few different sets of company eyes, we see that plasma's use has grown from a lab curiosity or simply a wetting tool to a sophisticated method for complete surface re-engineering. Many medical device companies have the equipment in house or are using resources through vendors such as PTS and 4th State. Plasma processing in the Bay Area has become a critical tool for providing functionality for attaching a myriad of biological coatings; providing tailored nano-scale coatings for chemical resistance and lubricity; continued importance in modification of materials for genomics research; and growing modification of point-of-care diagnostic devices. We anticipate that plasma surface modification will become as important a tool to the biosciences as it has become synonymous to the manufacture of semiconductor devices. 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